ArcticCrusher Posted January 2, 2023 Share Posted January 2, 2023 Nothing to see. Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 2, 2023 Share Posted January 2, 2023 15 hours ago, Jimmy Snacks said: IDGAF about proving shit to you…you’re an annoying bullshitting windbag that lectures strangers yet can’t keep his own house in order. 14 hours ago, awful knawful said: The Twitter Twat has spoken 😂 Put up or shut up. Quote Link to comment Share on other sites More sharing options...
akvanden Posted January 2, 2023 Share Posted January 2, 2023 12 minutes ago, ArcticCrusher said: Nothing to see. Wow, that’s like, a lot of people. I guess I should consider myself fortunate out of the all my neighbors, family, friends, coworkers, etc, no one has. Several did die from Covid, in 2020 though. Quote Link to comment Share on other sites More sharing options...
toslow Posted January 2, 2023 Share Posted January 2, 2023 (edited) 8 minutes ago, akvanden said: Wow, that’s like, a lot of people. I guess I should consider myself fortunate out of the all my neighbors, family, friends, coworkers, etc, no one has. Several did die from Covid, in 2020 though. We still don't know the long term effects of the vaccines, so there is that Edited January 2, 2023 by toslow Quote Link to comment Share on other sites More sharing options...
awful knawful Posted January 2, 2023 Share Posted January 2, 2023 31 minutes ago, ArcticCrusher said: Put up or shut up. You put up, anything but Twitter, for once. You stupid cunt. 1 Quote Link to comment Share on other sites More sharing options...
akvanden Posted January 2, 2023 Share Posted January 2, 2023 11 minutes ago, toslow said: We still don't know the long term effects of the vaccines, so there is that Maybe Rasmussen will ask ‘how many do you think will die’ in another poll so we can find out. Quote Link to comment Share on other sites More sharing options...
toslow Posted January 2, 2023 Share Posted January 2, 2023 1 minute ago, akvanden said: Maybe Rasmussen will ask ‘how many do you think will die’ in another poll so we can find out. lets give it a couple more yrs and see how it plays out Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 2, 2023 Share Posted January 2, 2023 2 hours ago, awful knawful said: You put up, anything but Twitter, for once. You stupid cunt. Stick to the cbc. Maybe try and pull your head out from Smales asshole. Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 2, 2023 Share Posted January 2, 2023 2 hours ago, akvanden said: Wow, that’s like, a lot of people. I guess I should consider myself fortunate out of the all my neighbors, family, friends, coworkers, etc, no one has. Several did die from Covid, in 2020 though. 80 million people know someone who died from the vax, you don't know shit. What a surprise. Do you still believe this cunt that you don't get covid if your are vaxxed? 1 Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 2, 2023 Share Posted January 2, 2023 It just means the vax is working. “workers who received more doses were at higher risk of getting sick. Those who received three more doses were 3.4 times as likely to get infected as the unvaccinated” Quote Link to comment Share on other sites More sharing options...
Platinum Contributing Member Jimmy Snacks Posted January 2, 2023 Platinum Contributing Member Share Posted January 2, 2023 23 minutes ago, ArcticCrusher said: Stick to the cbc. Maybe try and pull your head out from Smales asshole. Quote Link to comment Share on other sites More sharing options...
awful knawful Posted January 2, 2023 Share Posted January 2, 2023 3 hours ago, ArcticCrusher said: Stick to the cbc. Maybe try and pull your head out from Smales asshole. CBC is your pal Trudeau's station. Try using any other source besides Twitter. I triple dog dare you! Canadian Ben 🖕👍 Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 2, 2023 Share Posted January 2, 2023 One of the side effects of the vax is wait for it . . . . . Covid. 1 Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 2, 2023 Share Posted January 2, 2023 25 minutes ago, awful knawful said: CBC is your pal Trudeau's station. Try using any other source besides Twitter. I triple dog dare you! Canadian Ben 🖕👍 Still learning I see. Quote Link to comment Share on other sites More sharing options...
Deephaven Posted January 2, 2023 Share Posted January 2, 2023 51 minutes ago, ArcticCrusher said: Still learning I see. When are you going to? Still posting bunk links. When will you learn to think? Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 3, 2023 Share Posted January 3, 2023 For those who took AZ. Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 3, 2023 Share Posted January 3, 2023 29 minutes ago, Deephaven said: When are you going to? Still posting bunk links. When will you learn to think? What do you think the Fauci drop is gonna reveal? Besides your a fucking idiot. 1 Quote Link to comment Share on other sites More sharing options...
XCR1250 Posted January 3, 2023 Share Posted January 3, 2023 HEALTH CARE Once-favored Covid drugs ineffective on Omicron may be putting millions at risk While antiviral pills are plentiful and remain an option for some with weak immune systems, they won’t work for everyone — Pfizer’s Paxlovid interacts with many widely prescribed drugs. The Biden administration has strongly promoted oral antiviral regimens like Paxlovid, which debuted a year ago and marked a turning point in managing the virus for most Americans. | Stephanie Nano/AP By LAUREN GARDNER 01/01/2023 07:00 AM EST The lack of specialized Covid-19 treatments for people with weak immune systems has left millions of Americans with limited options if they get sick as the pandemic heads into an uncertain winter. Once heralded as game-changers for Covid patients considered at risk for getting seriously ill — one was used to treat then-President Donald Trump in 2020 — monoclonal antibodies are now largely ineffective against current Covid variants. Easier-to-administer antiviral drugs, such as Paxlovid, have largely taken their place but aren’t safe for all immune-compromised people because they interact with many other drugs. But the federal government funding that drove drug development in the early days of the pandemic has dried up, and lawmakers have rebuffed the Biden administration’s pleas for more. Without that, there’s little incentive for drugmakers to work on new antibody treatments that could be more effective. And without a government program like Operation Warp Speed to develop second-generation vaccines and treatments, at-risk patients could be in danger of developing severe cases of Covid and flooding hospitals when the U.S. health care system is already strained, thanks to an influx of patients with an array of respiratory illnesses, including flu and RSV. “Just because we have exited the emergency phase of the pandemic does not mean that Covid is over or that it no longer poses a danger,” said Leana Wen, a public health professor at George Washington University and former Baltimore health commissioner. “There are millions of Americans who are vulnerable to severe illness.” The FDA pulled authorizations for four antibody treatments in 2022 as Omicron and its myriad subvariants wiped out their effectiveness. The treatments were geared toward adult and pediatric patients with mild-to-moderate Covid who were considered at risk of developing severe disease and ending up hospitalized. While antiviral pills are plentiful and remain an option for some with weak immune systems, they won’t work for everyone — Pfizer’s Paxlovid interacts with many widely prescribed drugs. Monoclonal antibodies — which have been made by companies like Regeneron, Eli Lilly and Vir — are lab-created molecules designed to block a virus’ entry into human cells. But they must bind to the virus’ spike protein to neutralize it, and the coronavirus’ many mutations since its 2019 emergence have gradually rendered the available products ineffective. “It’s a bit risky to develop this,” said Arturo Casadevall of the Johns Hopkins Bloomberg School of Public Health, pointing to how quickly some Covid variants have surfaced before quickly receding. A massive spending bill that lawmakers passed before Christmas left out the administration’s $9 billion request for more money to fight the pandemic, meaning there are fewer dollars to be spread around to address emerging Covid needs. “Due to congressional inaction and a lack of funding, HHS does not have the resources it needs to fund the development of new treatments, and we could find ourselves with a very limited medicine cabinet at a time when we need more tools to combat Covid-19,” a department spokesperson told POLITICO, adding that HHS is working with providers and other groups “to ensure that Americans are able to take advantage of all available treatment options.” The Biden administration has strongly promoted oral antiviral regimens like Paxlovid, which debuted a year ago and marked a turning point in managing the virus for most Americans. Immunocompromised individuals — who are either born with immune-suppressing conditions or acquire them after organ transplants or by taking certain drugs — also may not mount sufficient immune responses after vaccination, making treatment options like antibody therapies a critical tool for them. MOST READ ‘To Hell with It’: A GOP Congressman Reflects on His One Term in Trump’s Party McCarthy relents on key conservative demand — but uncertainty remains over speaker bid Inside the Jan. 6 committee’s massive new evidence trove Outgoing Republican leaders condemn Santos, suggest resignation New data shows the folly of Trump’s crusade against early voting A CDC alert issued Dec. 20 to clinicians and public health professionals warned of the lack of viable monoclonal antibody treatments — including the diminished efficacy of a prophylactic antibody, Evusheld — and the availability of the antiviral options that to date have seen lackluster uptake. The agency urged providers to consult the National Institutes of Health’s Covid treatment guidelines for ways to potentially manage drug interactions with Paxlovid, such as temporary pauses or reductions in dose. Remdesivir, an antiviral administered intravenously, is another treatment option for the immunocompromised, but it requires infusions over three days in either hospital or outpatient settings. HHS is urging states to support its health departments and systems in setting up infusion clinics to expand access to remdesivir, especially on an outpatient basis, and is working with maker Gilead to broaden the types of providers eligible to buy the drug. Covid convalescent plasma remains an option for immunocompromised people who contract the virus, but its availability is scattershot across the country, Casadevall said. The treatment has pros and cons, he said — it’s less likely to be defeated by any one variant and can adapt to different strains, but it’s difficult to administer and requires blood-typing to be done for the recipient. Still, Casadevall said, the main issue is educational because its use has changed since the pandemic’s early days, when treatments were scarce. Some hospital systems, like Hopkins, use it routinely, while some doctors don’t know plasma is still an option, he said. The FDA has authorized the emergency use of convalescent plasma containing high Covid antibody levels for immunocompromised patients. But NIH has remained neutral on the treatment in that population, which Janet Handal, president of the Transplant Recipients and Immunocompromised Patient Advocacy Group, says has led to some hospitals balking at administering it. NIH spokesperson Renate Myles pointed to the agency’s treatment guidelines for Covid, which are developed by an expert panel. The recommendations for Covid convalescent plasma, last updated on Dec. 1, say there’s “insufficient evidence” to recommend for or against the treatment’s use in immunocompromised patients, while noting some panel members would use plasma to treat an immunocompromised person “with significant symptoms attributable to COVID-19 and with signs of active [viral] replication and who is having an inadequate response to available therapies.” “In these cases, clinicians should attempt to obtain high-titer [Covid convalescent plasma] from a vaccinated donor who recently recovered from Covid-19 likely caused by a … variant similar to the variant causing the patient’s illness,” the guidelines say. Casadevall, who leads the Covid-19 Convalescent Plasma Project, says NIH’s stance on plasma is inconsistent with its previous recommendations of monoclonal antibodies, which were made without clinical efficacy data, since Covid antibodies are the active component in both therapies. He led a petition earlier this month — signed by several doctors, including past and current presidents of the Infectious Diseases Society of America — asking NIH to change its recommendations. Handal’s group also has asked the NIH and the White House to convene a meeting with scientists on the issue. “To just not be having a dialogue about it is infuriating to us,” Handal said. “People are dying while people are just going through this bureaucratic dance.” The FDA and European Medicines Agency held a virtual workshop this month to bring doctors, industry and regulators together to discuss supporting novel monoclonal antibody treatments. “The FDA is committed to working with industry sponsors to expedite the development of new drug products to meet unmet needs, such as the need for new preventive therapies for immune-suppressed patients who are unlikely to respond to vaccination,” an agency spokesperson said. In the meantime, Regeneron spokesperson Tammy Allen said the company, whose antibody cocktail’s use was limited in January, is committed to evaluating antibody treatment options as the coronavirus evolves. “We believe monoclonal antibodies have played an important role in the COVID-19 pandemic to date and may again in the future, particularly among people with immunocompromising conditions,” Allen said. Vir, which partnered with GSK on sotrovimab, continues to study whether the treatment could work against emerging variants and is also evaluating next-generation antibodies and small-molecule therapies, said spokesperson Carly Scaduto. Still, pharmaceutical companies may be more inclined — both financially and practically — to pursue developing better antiviral pills that pose fewer drug interactions and are easier to administer, said Jason Gallagher, a clinical pharmacy specialist in infectious diseases at Temple University Hospital. Antivirals also hold up better against an ever-changing virus, he added. “There’s way more money in Paxlovid than there is in any monoclonal” antibody treatment, Gallagher said, and it may take incentives to drugmakers to encourage their development. “They’re not going to make anyone really rich.” Quote Link to comment Share on other sites More sharing options...
awful knawful Posted January 3, 2023 Share Posted January 3, 2023 1 hour ago, ArcticCrusher said: Still learning I see. I am every day. You, not so much. If I got slapped around everyday, like Deephaven does to you, I'd have learned already. Like a retarded puppy..... 1 Quote Link to comment Share on other sites More sharing options...
awful knawful Posted January 3, 2023 Share Posted January 3, 2023 34 minutes ago, ArcticCrusher said: What do you think the Fauci drop is gonna reveal? Besides your a fucking idiot. "You're" a fucking idiot. 😉 Quote Link to comment Share on other sites More sharing options...
Deephaven Posted January 3, 2023 Share Posted January 3, 2023 That's not nice to dumb puppies Quote Link to comment Share on other sites More sharing options...
f7ben Posted January 3, 2023 Share Posted January 3, 2023 (edited) 3 minutes ago, awful knawful said: I am every day. You, not so much. If I got slapped around everyday, like Deephaven does to you, I'd have learned already. Like a retarded puppy..... You dumbass mindless retarded piece of fucking shit. You’ve never been right a single time yet here you are still posting. dumbass fucking faggot , have a little dignity and kill your self you worthless retard Edited January 3, 2023 by f7ben Quote Link to comment Share on other sites More sharing options...
awful knawful Posted January 3, 2023 Share Posted January 3, 2023 1 minute ago, f7ben said: You dumbass mindless retarded piece of fucking shit. You’ve never been right a single time yet here you are still posting. dumbass fucking faggot , have a little dignity and kill your self you worthless retard You're the expert in being wrong you hooknosed Jew, foreskin munching, semen swallowing queer. Quote Link to comment Share on other sites More sharing options...
akvanden Posted January 3, 2023 Share Posted January 3, 2023 Quote Link to comment Share on other sites More sharing options...
ArcticCrusher Posted January 3, 2023 Share Posted January 3, 2023 Oh noos. 2 Quote Link to comment Share on other sites More sharing options...
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