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3 more studies on the effectiveness of Hydroxychloroquine.


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5 minutes ago, spin_dry said:

 Or one peer reviewed study has determined effectiveness. You post all anecdotal reports. 

Show me where they say they aren't peer reviewed.  

 

 

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Just now, spin_dry said:

Show me where they are. 

The study was published today in the International Journal of Infectious Diseases, the peer-reviewed, open-access online publication of the International Society of Infectious Diseases (ISID.org).

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10 minutes ago, Mainecat said:

Bob from Bumfuck, Idaho says it’s safe

Henry Ford Medical System and the Journal of General Internal Medicine is now bob from Bumfuck, Idaho.  :lol:  Honestly do you two think before you post?

The Journal of General Internal Medicine is a monthly peer-reviewed medical journal established in 1986 and covering internal medicine. It is published by Springer Nature and is the official journal of the Society of General Internal Medicine. According to the Journal Citation Reports, the journal has a 2017 impact factor of 4.001.[1] It is an official journal of the Society of General Internal Medicine.

Editors-in-chief[edit]

The following persons have been editors-in-chief of the journal::

  • 1986-1989 Robert H, Fletcher & Suzanne W. Fletcher
  • 1990-1994 David C. Dale
  • 1995-1999 Sankey V. Williams
  • 2000-2004 Eric Bass
  • 2004-2009 William Tierney & Martha Gerrity
  • 2009-2017 Richard Kravitz & Mitch Feldman

The current (2017-2022) editors-in-chief are Steve Asch (Stanford University), Carol Bates (Harvard University), and Jeffrey Jackson (Medical College of Wisconsin).

 

 

Edited by Highmark
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We know spin's medical expertise as an uneducated local clinic social worker is much better than say Harvard Medical school.  :lol:  

https://www.health.harvard.edu/diseases-and-conditions/treatments-for-covid-19

Are chloroquine/hydroxychloroquine and azithromycin safe and effective for treating COVID-19?

Early reports from China and France suggested that patients with severe symptoms of COVID-19 improved more quickly when given chloroquine or hydroxychloroquine. Some doctors were using a combination of hydroxychloroquine and azithromycin with some positive effects.

Hydroxychloroquine and chloroquine are primarily used to treat malaria and several inflammatory diseases, including lupus and rheumatoid arthritis. Azithromycin is a commonly prescribed antibiotic for strep throat and bacterial pneumonia. Both drugs are inexpensive and readily available.

Hydroxychloroquine and chloroquine have been shown to kill the COVID-19 virus in the laboratory dish. The drugs appear to work through two mechanisms. First, they make it harder for the virus to attach itself to the cell, inhibiting the virus from entering the cell and multiplying within it. Second, if the virus does manage to get inside the cell, the drugs kill it before it can multiply.

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One drug that has received a lot of attention is the antiviral drug remdesivir. That's because the coronavirus that causes COVID-19 is similar to the coronaviruses that caused the diseases SARS and MERS

:news:   

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

This article has been cited by other articles in PMC.
 

Abstract

Background

Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

Results

We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.

Conclusion

Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.

Keywords: severe acute respiratory syndrome coronavirus, chloroquine, inhibition, therapy
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10 minutes ago, Highmark said:

Henry Ford Medical System and the Journal of General Internal Medicine is now bob from Bumfuck, Idaho.  :lol:  Honestly do you two think before you post?

The Journal of General Internal Medicine is a monthly peer-reviewed medical journal established in 1986 and covering internal medicine. It is published by Springer Nature and is the official journal of the Society of General Internal Medicine. According to the Journal Citation Reports, the journal has a 2017 impact factor of 4.001.[1] It is an official journal of the Society of General Internal Medicine.

Editors-in-chief[edit]

The following persons have been editors-in-chief of the journal::

  • 1986-1989 Robert H, Fletcher & Suzanne W. Fletcher
  • 1990-1994 David C. Dale
  • 1995-1999 Sankey V. Williams
  • 2000-2004 Eric Bass
  • 2004-2009 William Tierney & Martha Gerrity
  • 2009-2017 Richard Kravitz & Mitch Feldman

The current (2017-2022) editors-in-chief are Steve Asch (Stanford University), Carol Bates (Harvard University), and Jeffrey Jackson (Medical College of Wisconsin).

 

 

Let’s be honest about these remarkable findings from Henry Ford medical. What’s the percentage of the placebo effect? 
 

The study found about 20% of patients treated with a combination of hydroxychloroquine and azithromycin died and 22% who were treated with azithromycin alone compared with the 26% of patients who died after not being treated with either medication. 

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1 minute ago, spin_dry said:

Let’s be honest about these remarkable findings from Henry Ford medical. What’s the percentage of the placebo effect? 
 

The study found about 20% of patients treated with a combination of hydroxychloroquine and azithromycin died and 22% who were treated with azithromycin alone compared with the 26% of patients who died after not being treated with either medication. 

So a 23% reduction is not significant when treating the most vulnerable?  :lol:

  

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CONCLUSIONS

In this retrospective study of over 6000 ambulatory and hospitalized patients with COVID-19 in the New York City metropolitan area, age, male sex, tachypnea, low systolic blood pressure, low peripheral oxygen saturation, impaired renal function, elevated IL-6, elevated D-dimer, and elevated troponin were found to be risk factors for mortality. Hydroxychloroquine use was associated with decreased mortality.

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15 minutes ago, F3600 said:

Jesus the boot stomping going on in here.

 

13 minutes ago, ArcticCrusher said:

Time for spin to tag in his alter ego.

We all know Spin's type right?   Likely ran into them at some point of your life especially if you've spent any time in a college town.

50-60's years old.   Hipster doofus almost Deadhead type.   Hangs around younger people so he can seem so much smarter and sophisticated in life than them even though he hasn't accomplished shit.   Likely has a ponytail maybe a goatee or mustache and lives some faux elitists liberal lifestyle.      

Didn't he use to make awkward comments about young woman...almost girls.   Fits right in that same profile. 

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4 minutes ago, Highmark said:

 

We all know Spin's type right?   Likely ran into them at some point of your life especially if you've spent any time in a college town.

50-60's years old.   Hipster doofus almost Deadhead type.   Hangs around younger people so he can seem so much smarter and sophisticated in life than them even though he hasn't accomplished shit.   Likely has a ponytail and lives some faux elitists liberal lifestyle.      

Oh yah, I know the type.:lol:

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