My wife lived in Italy for 2 years, she mentioned many of the same places you did. Didn’t plan on going into Naples, just wanted to see my Dad’s town (Casa Lattico) which is near Naples.
My family (cousins) have a place in Sicily on the sea. I plan on hanging around there a few days as well as checking out my moms town that she grew up in.
I have no interest in Venice or Rome or any of the other tourist spots at all. But as I said I’m sure the others will.