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COVID Brain Damage


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2 minutes ago, XC.Morrison said:

I know that many people think this is nothing more serious than a cold and nothing will change their minds but this virus brings with it complications and conditions doctors have not seen before with other viruses...strokes, blood clots, heart, lung and kidney issues along with what you posted.

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21 minutes ago, Jimmy Snacks said:

I know that many people think this is nothing more serious than a cold and nothing will change their minds but this virus brings with it complications and conditions doctors have not seen before with other viruses...strokes, blood clots, heart, lung and kidney issues along with what you posted.

Quite the amazing organism.   

Funny how new things seem to "pop up" every time we try and get back to some sort of normal and new cases appear.  5 months into this and now they are warning us of brain damage and hallucinations. :lmao:  

That doesn't strike you as odd at all?   When they could no longer scare us with the kids are getting sick and dying because they didn't have enough proof this pops up.   

Edited by Highmark
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2 minutes ago, Jimmy Snacks said:

I know that many people think this is nothing more serious than a cold and nothing will change their minds but this virus brings with it complications and conditions doctors have not seen before with other viruses...strokes, blood clots, heart, lung and kidney issues along with what you posted.

True.  And even if it were just a cold or flu, I fucking hate those.  Every time I get a cold there’s usually a 6 week minimum dry hacking cough and my Vick’s and Halls budget starts to look like something from Capitol Hill.  Honestly, I think a lot of the focus on hand hygiene and regular sterilization schedules are stuff we should have been doing all along and I hope maybe will be habits that we carry forward from this if it also reduces occurrences of other stuff spreading around.  

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Oops.   I spoke too soon.   They included the children.

 

A new study has warned that potentially deadly brain disorders may be a symptom of Covid-19, even in people with otherwise mild disease.

The research published today in the journal Brain, looked at 40 adult patients with Covid-19 in the U.K., finding that they showed symptoms of a wide range of serious brain diseases. Many of the patients had only mild typical Covid-19 symptoms such as fever or respiratory issues and for some, their neurological symptoms were the only sign they were sick.

One 55-year old woman with no known current or historical mental illness was admitted to hospital with recognized Covid-19 symptoms including fever, cough and muscle aches. She was discharged after two weeks, having been treated with oxygen, but four days later her husband reported she was confused and behaving strangely. She then experienced hallucinations, reporting seeing lions and monkeys in her house, and became delusional and aggressive with her family and hospital staff. She was treated with anti-psychotic medication and her symptoms improved over the course of three weeks, although the study does not confirm whether she made a full recovery.

Other neurological issues experienced by the Covid-19 patients, who ranged in age from 16-85, included more cases of delirium or psychosis, strokes and problems with peripheral nerves found in extremities like hands and feet.

 

Particularly worryingly, 9 patients were diagnosed with a form of Acute Demyelinating Encephalomyelitis (ADEM), where the immune system is thought to attack myelin, the insulating covering of nerves in the central nervous system. If myelin is absent or not thick enough, nerves lose the ability to effectively transmit information and a wide range of symptoms including paralysis and cognitive issues can result. ADEM is rare, but is almost always found in children after viral infections, not adults as was seen in this study.

A 47-year old woman experienced a week of typical Covid-19 symptoms, but then experienced neurological problems and was diagnosed with ADEM. Her brain eventually became so swollen that surgeons had to remove part of her skull to relieve the pressure.

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21 minutes ago, Highmark said:

Quite the amazing organism.   

Funny how new things seem to "pop up" every time we try and get back to some sort of normal and new cases appear.  5 months into this and now they are warning us of brain damage and hallucinations. :lmao:  

That doesn't strike you as odd at all?   When they could no longer scare us with the kids are getting sick and dying because they didn't have enough proof this pops up.   

No it doesn’t surprise me as Covid 19 is a new variant plus I don’t buy into conspiracy nonsense.

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Just now, Jimmy Snacks said:

No it doesn’t surprise me as Covid 19 is a new variant plus I don’t buy into conspiracy nonsense.

Yes because the world and US medical community has be so honest and forthcoming to date on this.   Should I make you a list?

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Just now, Highmark said:

Yes because the world and US medical community has be so honest and forthcoming to date on this.   Should I make you a list?

OK...so nobody is suffering from any of these issues because of Covid 19...you can save your list. I’ll believe what I believe.

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11 minutes ago, Jimmy Snacks said:

OK...so nobody is suffering from any of these issues because of Covid 19...you can save your list. I’ll believe what I believe.

Remember the Kawasaki like syndrome this was supposedly causing in children?   Popped up in articles in mid May just when states were starting to open back up.   Try and find a recent article on it.   They all seem to stop by mid June.  :lol:  

Thing is they've already admitted to a number of lies.   Masks don't work.   Masks work we just wanted to save them for HC workers.   Want more?

Intentional or not they jump to conclusion and show us any little thing to scare us.

Hydroxychloroquine ring a bell?   You know who wrote those two articles.....the same person.  

hydroxy-cnn.jpg

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the normalizing of the of pushing vaccines is coming on strong.   i just saw yet ANOTHER new one, this one for a shingles vaccine.  they should have all the cows lined up nicely by the time they release a covid shot.

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Imagine taking a CHEAP drug that's under a dollar a dose and has proven to work in studies all the way back in 2005 against Corona virus' and saying it doesn't all because a President they don't like mentions it.    What replaces it.   One that is $2600 a dose and has some pretty interesting investors to the company that makes it.    This should be the story of the century. 

They claim its deadly yet almost ANYONE traveling to a known Malaria area is prescribed it.   

Fuck people open your eyes.  Trump made the claims on its effectiveness because of it working and past studies.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/

Abstract

Background

Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

Results

We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.

Conclusion

Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.

Keywords: severe acute respiratory syndrome coronavirus, chloroquine, inhibition, therapy

Background

Severe acute respiratory syndrome (SARS) is an emerging disease that was first reported in Guangdong Province, China, in late 2002. The disease rapidly spread to at least 30 countries within months of its first appearance, and concerted worldwide efforts led to the identification of the etiological agent as SARS coronavirus (SARS-CoV), a novel member of the family Coronaviridae [1]. Complete genome sequencing of SARS-CoV [2,3] confirmed that this pathogen is not closely related to any of the previously established coronavirus groups. Budding of the SARS-CoV occurs in the Golgi apparatus [4] and results in the incorporation of the envelope spike glycoprotein into the virion. The spike glycoprotein is a type I membrane protein that facilitates viral attachment to the cellular receptor and initiation of infection, and angiotensin-converting enzyme-2 (ACE2) has been identified as a functional cellular receptor of SARS-CoV [5]. We have recently shown that the processing of the spike protein was effected by furin-like convertases and that inhibition of this cleavage by a specific inhibitor abrogated cytopathicity and significantly reduced the virus titer of SARS-CoV [6].

Due to the severity of SARS-CoV infection, the potential for rapid spread of the disease, and the absence of proven effective and safe in vivo inhibitors of the virus, it is important to identify drugs that can effectively be used to treat or prevent potential SARS-CoV infections. Many novel therapeutic approaches have been evaluated in laboratory studies of SARS-CoV: notable among these approaches are those using siRNA [7], passive antibody transfer [8], DNA vaccination [9], vaccinia or parainfluenza virus expressing the spike protein [10,11], interferons [12,13], and monoclonal antibody to the S1-subunit of the spike glycoprotein that blocks receptor binding [14]. In this report, we describe the identification of chloroquine as an effective pre- and post-infection antiviral agent for SARS-CoV. Chloroquine, a 9-aminoquinoline that was identified in 1934, is a weak base that increases the pH of acidic vesicles. When added extracellularly, the non-protonated portion of chloroquine enters the cell, where it becomes protonated and concentrated in acidic, low-pH organelles, such as endosomes, Golgi vesicles, and lysosomes. Chloroquine can affect virus infection in many ways, and the antiviral effect depends in part on the extent to which the virus utilizes endosomes for entry. Chloroquine has been widely used to treat human diseases, such as malaria, amoebiosis, HIV, and autoimmune diseases, without significant detrimental side effects [15]. Together with data presented here, showing virus inhibition in cell culture by chloroquine doses compatible with patient treatment, these features suggest that further evaluation of chloroquine in animal models of SARS-CoV infection would be warranted as we progress toward finding effective antivirals for prevention or treatment of the disease.

Results

Preinfection chloroquine treatment renders Vero E6 cells refractory to SARS-CoV infection

In order to investigate if chloroquine might prevent SARS-CoV infection, permissive Vero E6 cells [1] were pretreated with various concentrations of chloroquine (0.1–10 μM) for 20–24 h prior to virus infection. Cells were then infected with SARS-CoV, and virus antigens were visualized by indirect immunofluorescence as described in Materials and Methods. Microscopic examination (Fig. (Fig.1A)1A) of the control cells (untreated, infected) revealed extensive SARS-CoV-specific immunostaining of the monolayer. A dose-dependant decrease in virus antigen-positive cells was observed starting at 0.1 μM chloroquine, and concentrations of 10 μM completely abolished SARS-CoV infection. For quantitative purposes, we counted the number of cells stained positive from three random locations on a slide. The average number of positively stained control cells was scored as 100% and was compared with the number of positive cells observed under various chloroquine concentrations (Fig. (Fig.1B).1B). Pretreatment with 0.1, 1, and 10 μM chloroquine reduced infectivity by 28%, 53%, and 100%, respectively. Reproducible results were obtained from three independent experiments. These data demonstrated that pretreatment of Vero E6 cells with chloroquine rendered these cells refractory to SARS-CoV infection

Edited by Highmark
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Just now, Snake said:

Fucking no minds like these idiots will be fighting over who gets vaccinated first... :lol:

Whats so amazing is indisputable evidence is there and people....sheep really refuse to acknowledge it. 

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Just now, Highmark said:

Whats so amazing is indisputable evidence is there and people....sheep really refuse to acknowledge it. 

Whatever completes their lives....

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43 minutes ago, Highmark said:

Quite the amazing organism.   

Funny how new things seem to "pop up" every time we try and get back to some sort of normal and new cases appear.  5 months into this and now they are warning us of brain damage and hallucinations. :lmao:  

That doesn't strike you as odd at all?   When they could no longer scare us with the kids are getting sick and dying because they didn't have enough proof this pops up.   

Actually early on people complained of hallucinations and weird dreams.  

My SIL and my wife's cousin are both ICU Covid nurses, SIL has 34 years ICU and  the cousin has about 32, they both say this is a strange and scary thing worst they have ever seen. 

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2 minutes ago, 1jkw said:

Actually early on people complained of hallucinations and weird dreams.  

My SIL and my wife's cousin are both ICU Covid nurses, SIL has 34 years ICU and  the cousin has about 32, they both say this is a strange and scary thing worst they have ever seen. 

Yeah and my buddies daughter nanny's for a doctor at a University Hospital and he told her not to worry about it when her roommate tested positive and continue to come and nanny.   His comment was everyone's going to get it and its no big deal. 

For every horror story from the med field there is another doctor or nurse saying something different.  

Remember when CBS used footage from another countries ICU claiming it was in the US?  :lol:  

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16 minutes ago, Highmark said:

Yeah and my buddies daughter nanny's for a doctor at a University Hospital and he told her not to worry about it when her roommate tested positive and continue to come and nanny.   His comment was everyone's going to get it and its no big deal. 

For every horror story from the med field there is another doctor or nurse saying something different.  

Remember when CBS used footage from another countries ICU claiming it was in the US?  :lol:  

Yeah tell that to my dead friends family, I'm sure they would love to hear how harmless it is. 

You Trump cult guys are sure amazing, countries all over the world shut down and it's all to get Trump.

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7 minutes ago, 1jkw said:

Yeah tell that to my dead friends family, I'm sure they would love to hear how harmless it is. 

You Trump cult guys are sure amazing, countries all over the world shut down and it's all to get Trump.

I never said it wasn't serious an I'm sorry for your friend.

Not to get Trump.....get his ideals and those that believe in them.   He is merely one of the spokespersons.   Keeping the people down and changing to more controlling govt is not a phenomenon just here dude.  He just woke it up or tapped into it in the US and around the world and they are terrified of it. 

 

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5 minutes ago, 1jkw said:

Yeah tell that to my dead friends family, I'm sure they would love to hear how harmless it is. 

You Trump cult guys are sure amazing, countries all over the world shut down and it's all to get Trump.

What would you have us do?

No dems wanted to close the border.

No dems wanted quarantine. 

Dems were encouraging people to go out.

Dems said thousands in the street was perfectly ok.

And now you want us to feel for your friend? Tell you what... I do.

But try putting the fucking blame where it ought to go.

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2 minutes ago, Highmark said:

I never said it wasn't serious an I'm sorry for your friend.

Not to get Trump.....get his ideals and those that believe in them.   He is merely one of the spokespersons.   Keeping the people down and changing to more controlling govt is not a phenomenon just here dude.  

 

Thanks. 

Socialism? That seems to be his ideal now, debt and deficit spending was before for sure.

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Just now, 1jkw said:

Thanks. 

Socialism? That seems to be his ideal now, debt and deficit spending was before for sure.

The welfare state is only part of socialism.   Its not the whole thing.   The much more dangerous part is the control.   As mentioned before I don't agree with what the admin has done but again this is something we've never seen before.  Other recessions were natural.....this is one govt shutting down business' caused.  

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2 minutes ago, Snake said:

What would you have us do?

No dems wanted to close the border.

No dems wanted quarantine. 

Dems were encouraging people to go out.

Dems said thousands in the street was perfectly ok.

And now you want us to feel for your friend? Tell you what... I do.

But try putting the fucking blame where it ought to go.

Follow simple guidelines, wash hands stay home if sick, wear a mask when in stores ect.

Early on for the next 3. 

Thanks. 

Plenty of blame to go around.  

This isn't some worldwide scheme to get Trump like many feel it is.

 

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4 minutes ago, 1jkw said:

Follow simple guidelines, wash hands stay home if sick, wear a mask when in stores ect.

Early on for the next 3. 

Thanks. 

Plenty of blame to go around.  

This isn't some worldwide scheme to get Trump like many feel it is.

 

No one is making that full on claim.   However, its simply useful to use to try and destroy him and movement he has awoken.   As is the fake, salacious labeling of him as a racist, as was the whole Russia collusion and obstruction of justice perpetrated by very high levels of our own govt.   Trump was never a racist before he ran as a Republican and well the whole Russia collusion thing.....if you bought into that  you are no different than them.    

Out of all the cases of police brutality and yes even murder why now has it caused what it has?   Couldn't possibly be because its being pushed by higher agenda of communism or worse?   After all we know BLM is admitting they are led by trained Marxists and the goal is to destroy the US as we know it not just end police criminality.  

Edited by Highmark
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4 minutes ago, Highmark said:

No one is making that full on claim.   However, its simply useful to use to try and destroy him and movement he has awoken.   As is the fake, salacious labeling of him as a racist, as was the whole Russia collusion and obstruction of justice perpetrated by very high levels of our own govt.   Trump was never a racist before he ran as a Republican and well the whole Russia collusion thing.....if you bought into that  you are no different than them.    

No one is making that “full on claim”...so you believe the world is partially trying to get Trump? 🤣🤣
BTW do some reading around here...there are absolutely a few  that are full on making the claim. 

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