This episode aired back in December but I just got around to watching it.
Some very interesting stuff about Psilocybin therapy and how it created some amazing change in people's lives. Some of them had transcendic experiences which were very beneficial and others had "Hell on Earth" type of experiences but in the end, most were happy they went thru the experience.
https://www.livescience.com/psilocybin-depression-breakthrough-therapy.html